Substance use screening is mandatory in every psychiatric encounter. Substances shape psychiatric presentation directly (intoxication, withdrawal, induced disorders), indirectly (drug interactions, adherence problems), and prognostically (treatment response, relapse risk). The patient who is using substances and not telling you is being treated for the wrong condition, often unsuccessfully.
Normalize the question. "I ask everyone about substance use — it's important for your medical care." The framing matters. Substance use is asked without judgment, with the same routineness as asking about sleep. The patient who senses judgment closes the door to honest disclosure quickly.
Ask category by category. Alcohol. Cannabis. Stimulants (cocaine, methamphetamine, prescription stimulants used outside prescription). Opioids (heroin, fentanyl, prescription opioids used outside prescription). Sedative-hypnotics (benzodiazepines, z-drugs misuse). Hallucinogens. Inhalants. Tobacco and nicotine. Each category specifically; "any substances?" is too vague.
Quantify directly. "How many drinks in a typical week?" rather than "Do you drink?" "Occasionally" might mean monthly or might mean nightly; you need numbers. Days per week using cannabis, joints per day, drinks per week. Specific numbers matter.
Ask about prescription misuse specifically. The patient who answers "no" to "do you use illegal drugs" may take their spouse's Xanax, double their own oxycodone, or buy ADHD medication from a friend. Frame the question to capture these patterns: "Do you ever take medications differently than prescribed, or take medications that weren't prescribed to you?"
Pattern matters. Daily versus binge versus social. Recent change in pattern. Last use date. Withdrawal history. Prior treatment attempts. Family history of substance use disorder. Patient's own framing — does the patient see use as a problem?
Don't react with visible judgment when the patient discloses. The face that registers shock, disappointment, or worry tells the patient not to share more. Document specifics; bring nothing else to the disclosure beyond clinical attention.